Market Expansion

Market expansion opportunities for Melt-300 and our other product candidates include an estimated over 100 million procedures with durations from 10 minutes to 2 hours. Our formulation has the potential to replace IV sedation in medical interventions such as emergency room procedures, dental, plastic surgery, endoscopic procedures, and MRI when claustrophobia is present.

Expansion Opportunities

Annual Procedures (US)

36 Million MRI22.3 Million Dental19 million Emergency Room18.5 Million Endoscopic3.2 million Biopsies1.1 Million Plastic Surgery/Cosmetic1.1 million Women's Health1 million Minor Surgeries (for example: skin, bonebreaks)209 thousand Foot Surgeries102 million plus  Annual Market Opportunities


  1. Market Research Reports on Imaging and Clinical Markets. IMV Medical Information Division. Accessed March 6, 2020.
  2. Endodontic Treatment Statistics. American Association of Endodontists. Accessed March 6, 2020.
  3. Internal estimate based on data from: National Hospital Ambulatory Medical Care Survey: 2015 Emergency Department Summary Tables. 2015:34.
  4. US Market Report Suite for Gastrointestinal Endoscopic Devices 2017 – MedSuite. (2016, August 01).
  5. Voigt J, Mosier M. A powered bone marrow biopsy system versus manual methods: a systematic review and meta-analysis of randomised J Clin Pathol. 2013;66(9):792-796. doi:10.1136/jclinpath-2013-201605
  6. Jones TA, Radtke JP, Hadaschik B, Marks LS. Optimizing Safety and Accuracy of Prostate Biopsy. Curr Opin Urol. 2016;26(5):472-480. doi:10.1097/MOU.0000000000000310
  7. Elmore JG, Longton GM, Carney PA, et al. Diagnostic Concordance Among Pathologists Interpreting Breast Biopsy Specimens. JAMA. 2015;313(11):1122-1132. doi:10.1001/jama.2015.1405
  8. Internal estimate  based on Market Research data on file conducted by Triangle Research Group of NC. Retrieved September, 2019.
  9. Sklavos MM, Spracklen CN, Saftlas AF, Pinto LA. Does Loop Electrosurgical Excision Procedure of the Uterine Cervix Affect Anti-Müllerian Hormone Levels? Biomed Res Int. 2014;2014. doi:10.1155/2014/875438
  10. Chan LM, Westhoff CL. Tubal sterilization trends in the United States. Fertil Steril. 2010;94(1):1-6. doi:10.1016/j.fertnstert.2010.03.029
  11. Internal estimate based on data from: Amin S, Achenbach SJ, Atkinson EJ, Khosla S, Melton LJ. Trends in Fracture Incidence: A Population-Based Study Over 20 Years. J Bone Miner Res. 2014;29(3):581-589. doi:10.1002/jbmr.2072
  12. Vanore The “BONE ANCHOR SIGN:” Sign of Failure of Bunion Surgery. The Podiatry Institute. 2015:31-35.